Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8260983 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2013 | 14 Pages |
Abstract
⺠PDN affects Cav3.2 and TRPV1 channels in small DRG neurons. ⺠Hyperalgesic PDN upregulated both Cav3.2 and TRPV1 channels. ⺠Hypoalgesic PDN downregulated Cav3.2 and TRPV1 channels. ⺠Upregulation of Cav3.2 and downregulation of TRPV1 channels under normalgesic PDN ⺠Increased T-type window current contributes to the resting [Ca2 +]i in diabetes.
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Authors
Eugen V. Khomula, Viacheslav Y. Viatchenko-Karpinski, Anya L. Borisyuk, Dmytro E. Duzhyy, Pavel V. Belan, Nana V. Voitenko,