| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8260996 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2013 | 14 Pages |
Abstract
⺠Upregulation of LCN2 is a reliable indicator of liver damage. ⺠LCN2 has significant hepato-protective effects in acute liver injury. ⺠LCN2 deficient mice show increased expression of inflammatory mediators. ⺠LCN2 deficient mice show sustained activation of STAT1, STAT3 and JNK pathways. âºLCN2 is not correlated to hepatic fibrosis but correlates to inflammation.
Keywords
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Authors
Erawan Borkham-Kamphorst, Eddy van de Leur, Henning W. Zimmermann, Karlin Raja Karlmark, Lidia Tihaa, Ute Haas, Frank Tacke, Thorsten Berger, Tak W. Mak, Ralf Weiskirchen,