| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8261045 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2013 | 10 Pages |
Abstract
⺠Quercetin improved mitochondrial dysfunctions in 3-NP induced rodent model of HD. ⺠Mitochondrial antioxidant status was improved on quercetin supplementation. ⺠Quercetin ameliorated behavioral deficits along with histopathological changes. ⺠A putative role of quercetin supplementation in HD management is suggested.
Keywords
DTNB5,5-dithiobis-2-nitrobenzoic acidMDA3-NPTSHNBTSDHCAT3-nitropropionic acidPSHROS/RNSnitroblue tetrazoliumHuntington's diseaseTotal thiolsNeurodegenerationelectron transport chainSODSuperoxide dismutasesuccinate dehydrogenaseFlavonoidmalondialdehydeMitochondrionETcProtein thiolsCatalaseQuercetinReactive oxygen and nitrogen species
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Authors
Rajat Sandhir, Arpit Mehrotra,