Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8261120 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2013 | 12 Pages |
Abstract
⺠AdoHcy is a potent product inhibitor of AdoMet-dependent methyltransferases. ⺠AdoHcy accumulates in hyperhomocysteinemia. ⺠Yeast is an advantageous system to understand AdoHcy toxicity. ⺠Lipid metabolism is deregulated in response to AdoHcy accumulation.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Ageing
Authors
Oksana Tehlivets, Nermina Malanovic, Myriam Visram, Tea Pavkov-Keller, Walter Keller,