| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8261144 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2013 | 9 Pages |
Abstract
⺠MB is currently under study for neurodegenerative diseases. ⺠MB significantly affects the kinetics of PrP oligomerization. ⺠MB reduces the amount of PrP oligomer and completely suppresses fiber formation. ⺠NMR revealed that PrP hosts MB in a surface cleft. ⺠MB can be considered an anti-aggregation compound against proteinopathies.
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Authors
Paola Cavaliere, Joan Torrent, Stephanie Prigent, Vincenzo Granata, Kris Pauwels, Annalisa Pastore, Human Rezaei, Adriana Zagari,