Article ID Journal Published Year Pages File Type
8261191 Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2013 10 Pages PDF
Abstract
► HSPA12B protected brain from cerebral ischemia/reperfusion (I/R) injury. ► HSPA12B activated PI3K/Akt signaling in ischemic brains after cerebral I/R. ► Inhibition of PI3K abolished HSPA12B-induced protection against cerebral I/R. ► Thus, the neuroprotection of HSPA12B was mediated by PI3K/Akt activation.
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