Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8261205 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2013 | 9 Pages |
Abstract
⺠CpG-ODN administration attenuated ischemia/reperfusion-induced myocardial infarction. ⺠CpG-ODN improved cardiac function after myocardial reperfusion up to 14 days. ⺠CpG-ODN administration increased Akt and GSK-3β phosphorylation in the myocardium. ⺠PI3K inhibition or Akt deficiency abolished CpG-ODN-induced cardioprotection.
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Authors
Zhijuan Cao, Danyang Ren, Tuanzhu Ha, Li Liu, Xiaohui Wang, John Kalbfleisch, Xiang Gao, Race Kao, David Williams, Chuanfu Li,