Article ID Journal Published Year Pages File Type
8261241 Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2013 14 Pages PDF
Abstract
► We examine the effect of CYP2E1 inhibition against alcoholic cardiomyopathy. ► Diallyl sulfide alleviates ethanol intake-induced cardiac defect and apoptosis. ► CYP2E1 inhibition inhibits oxidative stress, activation of ASK-1 and JNK.
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Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
Preview
Inhibition of CYP2E1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction and apoptosis
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