| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8261361 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2012 | 9 Pages |
Abstract
⺠The PH3 HOGA mutations lead to unstable and inactive proteins. ⺠N-acetylneuraminate aldolase does not contribute to HOG cleavage. ⺠Glyoxylate reductase is inhibited by HOG. ⺠Glyoxylate reductase inhibition is one component of the molecular basis for PH3.
Keywords
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Authors
Travis J. Riedel, John Knight, Michael S. Murray, Dawn S. Milliner, Ross P. Holmes, W. Todd Lowther,