Article ID Journal Published Year Pages File Type
8261450 Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2012 8 Pages PDF
Abstract
▶ NADPH is an essential reducing equivalent for fat and cholesterol biosynthesis. ▶ IDPc has been proposed as a key enzyme for supplying cytosolic NADPH. ▶ Knockdown of IDPc by RNA interference inhibited adipogenesis and lipid biosynthesis.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
Preview
RNA interference targeting cytosolic NADP+-dependent isocitrate dehydrogenase exerts anti-obesity effect in vitro and in vivo
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