Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8261451 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2012 | 9 Pages |
Abstract
⺠After 4 months of STZ administration gastrocnemius IMF mitochondria functionality decreased. ⺠Increased mitochondria carbonylation levels were paralleled by decreased OXPHOS activity. ⺠Decreased mitochondria proteolysis was related with increased protein oxidation. ⺠AAA proteases activity and expression decreased in diabetic animals.
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Authors
Ana Isabel Padrão, Tiago Carvalho, Rui Vitorino, Renato M.P. Alves, Armando Caseiro, José Alberto Duarte, Rita Ferreira, Francisco Amado,