| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8261576 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2012 | 8 Pages |
Abstract
⺠HSF4 promotes DNA breaks repair through the regulation of Rad51 expression. ⺠HSF4 pathogenic mutations abolish the DNA damage repair ability of HSF4. ⺠Camptothecin inhibits the up-regulation of Rad51 levels by HSF4. ⺠Knock down of HSF4 in Zebrafish decrease Rad51 levels and DNA repair.
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Authors
Xiukun Cui, Jing Zhang, Rong Du, Lei Wang, Stephen Archacki, Yuexuan Zhang, Mingxiong Yuan, Tie Ke, Hui Li, Duanzhuo Li, Chang Li, David Wan-Cheng Li, Zhaohui Tang, Zhan Yin, Mugen Liu,