| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8261668 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2011 | 8 Pages |
Abstract
⺠Mitochondrial content is normal in type 2 diabetic myotubes ⺠Palmitate oxidation is decreased in type 2 diabetic myotubes compared to control myotubes only in condition of lipid overload ⺠ACC inactivation by palmitate is impaired in type 2 diabetic myotubes ⺠AICAR and metformin treatments do not activate AMPK or decrease lipid content in type 2 diabetic myotubes ⺠Mitochondrial inhibition by antimycin or metformin induce an increase in lipid content in control myotubes.
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Authors
Magali Kitzmann, Louise Lantier, Sophie Hébrard, Jacques Mercier, Marc Foretz, Celine Aguer,