| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8261693 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2011 | 12 Pages |
Abstract
âºThe consecutive stages of NAFLD can be recreated in time in an overfed mouse model. âºPparγ and Fgf21 are induced in the livers of HFLD-overfed mice only. âºSteatohepatitis coincides with obesity, hyperinsulinemia and loss of liver glycogen. âºSteatohepatitis coincides with the occurrence of hepatic endoplasmatic reticulum stress. âºAdipose tissue of overfed mice is inflamed and has reduced adiponectin expression.
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Authors
Ingrid C. Gaemers, Jan M. Stallen, Cindy Kunne, Christian Wallner, Jochem van Werven, Aart Nederveen, Wouter H. Lamers,