| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8261711 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2011 | 12 Pages |
Abstract
⺠Cav3 loss of expression triggered by Cav3 (P104L) form impairs Akt and p38 signalling in myoblasts. ⺠Cav3 (P104L) myoblasts display an immature cell and molecular signature. ⺠Loss of Cav3 at the plasma membrane perturbs TGF-beta pathways. ⺠Administration of IGF-1 or trichostatin A improves the differentiation of myoblasts harbouring Cav3 (P104L) form.
Keywords
PBSMMLV-RTMCKMyHCMLCbHLHIGF-1GAPDHPI3KFBSDMEMBSADMSOMAPKDulbecco's modified Eagle's mediumbovine serum albuminbasic helix-loop-helixinsulin-like growth factor-1Dimethylsulfoxidemyosin light chainMyosin heavy chainhorse serumfoetal bovine serumcytomegalovirusCMVmuscle creatine kinasephosphate buffer solutionmoloney murine leukemia virus reverse transcriptasemitogen-activated protein kinasesglyceraldehyde 3-phosphate dehydrogenase
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Authors
Elena Stoppani, Stefania Rossi, Elisabetta Meacci, Fabio Penna, Paola Costelli, Arianna Bellucci, Fiorella Faggi, Daniele Maiolo, Eugenio Monti, Alessandro Fanzani,