Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
826429 | Journal of Advanced Research | 2013 | 5 Pages |
Abstract
Michael addition reaction of the 2-amino-1,3,4-thiadiazole to chalcone as biselectrophile afforded 5,7-diphenyl-6-[1,3-diphenylpropan-1-on-3-yl][1,3,4]thiadiazolo[3,2-a]pyrimidine (3) instead of 5,7-diphenyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidine (5) via further Michael addition at C5 in pyrimidine moiety. The structure 3 was established through the aspect of ab initio calculations, elemental analysis and spectral data.
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Chemistry
Chemistry (General)
Authors
Wafaa S. Hamama, Moustafa A. Gouda, Mamdouh S. Soliman, Marwa H. Badr, Hanafi H. Zoorob,