Brain mitochondrial iron accumulates in Huntington's disease, mediates mitochondrial dysfunction, and can be removed pharmacologically

Article ID	Journal	Published Year	Pages	File Type
8265658	Free Radical Biology and Medicine	2018	41 Pages	PDF

Keywords

SDH trifluorocarbonylcyanide phenylhydrazone Trientine FCCP TET DFP TBARS ISC EGTA DFO Deferiprone Deferoxamine ROS Iron Alzheimer's disease Huntington's disease Parkinson's disease Neurodegeneration iron-sulfur cluster succinate dehydrogenase lactate dehydrogenase LDH thiobarbituric acid-reactive substances Mitochondria Reactive oxygen species

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Brain mitochondrial iron accumulates in Huntington's disease, mediates mitochondrial dysfunction, and can be removed pharmacologically

Authors

Sonal Agrawal, Julia Fox, Baskaran Thyagarajan, Jonathan H. Fox,