Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8267519 | Free Radical Biology and Medicine | 2016 | 38 Pages |
Abstract
- LC-MS/MS method for the simultaneous analysis of oxidized and reduced glutathione.
- The method is validated based on FDA guidelines in vitro and in vivo systems.
- Detection of glutathione in rare HSPCs and drug induced variations of GSH levels.
- ABCC1 expression alters intracellular glutathione concentrations within HSPCs.
- Evaluation of glutathione as a potential biomarker for hematopoietic malignancy.
Keywords
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Authors
Dustin Carroll, Diana Howard, Haining Zhu, Christian M. Paumi, Mary Vore, Subbarao Bondada, Ying Liang, Chi Wang, Daret K. St. Clair,