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A Western diet induced NAFLD in LDLR−/− mice is associated with reduced hepatic glutathione synthesis

Article ID Journal Published Year Pages File Type
8267623 Free Radical Biology and Medicine 2016 9 Pages PDF
Keywords
4-HNE4-hydroxynonenalNAFLDFSRDTTTBARSLFDGCsLC–MS/MSROSγ-glutamylcysteine synthetaseheavy waternonalcoholic steatohepatitisNonalcoholic fatty liver diseaseOxidative stressdithiothreitolLow fat dietWestern dietFluxmass spectrometerGas Chromatography Mass Spectrometrythiobarbituric acid reactive substancesfractional synthesis rateNash liquid chromatography–tandem mass spectrometryGlutathioneglutathione synthetaseReactive oxygen species
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
Preview
A Western diet induced NAFLD in LDLR−/− mice is associated with reduced hepatic glutathione synthesis
Authors
Ling Li, Guo-Fang Zhang, Kwangwon Lee, Rocio Lopez, Stephen F. Previs, Belinda Willard, Arthur McCullough, Takhar Kasumov,
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Journal
Free Radical Biology and Medicine
Journal: Free Radical Biology and Medicine
Related Categories
4-HNE
4-hydroxynonenal
NAFLD
FSR
DTT
TBARS
LFD
GCs
LC–MS/MS
ROS
γ-glutamylcysteine synthetase
heavy water
nonalcoholic steatohepatitis
Nonalcoholic fatty liver disease
Oxidative stress
dithiothreitol
Low fat diet
Western diet
Flux
mass spectrometer
Gas Chromatography Mass Spectrometry
thiobarbituric acid reactive substances
fractional synthesis rate
Nash
liquid chromatography–tandem mass spectrometry
Glutathione
glutathione synthetase
Reactive oxygen species
Ageing
Biochemistry
Biochemistry, Genetics and Molecular Biology (General)
Biophysics
Biotechnology
Cancer Research
Cell Biology
Clinical Biochemistry
Developmental Biology
Endocrinology
Genetics
Molecular Biology
Molecular Medicine
Physiology
Structural Biology
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