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Knockdown delta-5-desaturase promotes the formation of a novel free radical byproduct from COX-catalyzed ω-6 peroxidation to induce apoptosis and sensitize pancreatic cancer cells to chemotherapy drugs

Article ID Journal Published Year Pages File Type
8267718 Free Radical Biology and Medicine 2016 29 Pages PDF
Keywords
PBSPFBDGLAPUFAsdelta-5-desaturaseD5DCOXnc-Sicyclooxygenasedihomo-γ-linolenic acidArachidonic acidPolyunsaturated fatty acidsPancreatic cancer cell linesMass spectrometryPhosphate buffered salinePentafluorobenzylGas chromatography
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
Preview
Knockdown delta-5-desaturase promotes the formation of a novel free radical byproduct from COX-catalyzed ω-6 peroxidation to induce apoptosis and sensitize pancreatic cancer cells to chemotherapy drugs
Authors
Xiaoyu Yang, Yi Xu, Amanda Brooks, Bin Guo, Keith W. Miskimins, Steven Y. Qian,
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Journal
Free Radical Biology and Medicine
Journal: Free Radical Biology and Medicine
Related Categories
PBS
PFB
DGLA
PUFAs
delta-5-desaturase
D5D
COX
nc-Si
cyclooxygenase
dihomo-γ-linolenic acid
Arachidonic acid
Polyunsaturated fatty acids
Pancreatic cancer cell lines
Mass spectrometry
Phosphate buffered saline
Pentafluorobenzyl
Gas chromatography
Ageing
Biochemistry
Biochemistry, Genetics and Molecular Biology (General)
Biophysics
Biotechnology
Cancer Research
Cell Biology
Clinical Biochemistry
Developmental Biology
Endocrinology
Genetics
Molecular Biology
Molecular Medicine
Physiology
Structural Biology
Related Journals
Neurobiology of Aging
Revista Española de Geriatría y Gerontología
Ageing Research Reviews
Archives of Gerontology and Geriatrics
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Experimental Gerontology
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Journal of the Neurological Sciences
Maturitas
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Redox Biology
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