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Vitamin E metabolite 13′-carboxychromanols inhibit pro-inflammatory enzymes, induce apoptosis and autophagy in human cancer cells by modulating sphingolipids and suppress colon tumor development in mice

Article ID Journal Published Year Pages File Type
8267842 Free Radical Biology and Medicine 2016 10 Pages PDF
Keywords
LC3dhSphdhCerDihydroceramide desaturasedihydrosphingosine5-LOXSMaseazoxymethaneDEGsAOMCOXSPHDSS5-LipoxygenaseLC-MS/MScyclooxygenaseAutophagysphingomyelinsphingosinesphingolipidsphingomyelin synthasesphingomyelinaseApoptosisDihydroceramidemicrotubule-associated protein light chain 3CerceramideCancerdextran sodium sulfateSMSliquid chromatography tandem mass spectrometry
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
Preview
Vitamin E metabolite 13′-carboxychromanols inhibit pro-inflammatory enzymes, induce apoptosis and autophagy in human cancer cells by modulating sphingolipids and suppress colon tumor development in mice
Authors
Yumi Jang, Na-Young Park, Agnetha Linn Rostgaard-Hansen, Jianjie Huang, Qing Jiang,
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Journal
Free Radical Biology and Medicine
Journal: Free Radical Biology and Medicine
Related Categories
LC3
dhSph
dhCer
Dihydroceramide desaturase
dihydrosphingosine
5-LOX
SMase
azoxymethane
DEGs
AOM
COX
SPH
DSS
5-Lipoxygenase
LC-MS/MS
cyclooxygenase
Autophagy
sphingomyelin
sphingosine
sphingolipid
sphingomyelin synthase
sphingomyelinase
Apoptosis
Dihydroceramide
microtubule-associated protein light chain 3
Cer
ceramide
Cancer
dextran sodium sulfate
SMS
liquid chromatography tandem mass spectrometry
Ageing
Biochemistry
Biochemistry, Genetics and Molecular Biology (General)
Biophysics
Biotechnology
Cancer Research
Cell Biology
Clinical Biochemistry
Developmental Biology
Endocrinology
Genetics
Molecular Biology
Molecular Medicine
Physiology
Structural Biology
Related Journals
Neurobiology of Aging
Revista Española de Geriatría y Gerontología
Ageing Research Reviews
Archives of Gerontology and Geriatrics
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Experimental Gerontology
Journal of Geriatric Oncology
Journal of the Neurological Sciences
Maturitas
Mechanisms of Ageing and Development
Parkinsonism & Related Disorders
Redox Biology
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