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Platinum anti-cancer drugs: Free radical mechanism of Pt-DNA adduct formation and anti-neoplastic effect

Article ID Journal Published Year Pages File Type
8267878 Free Radical Biology and Medicine 2016 33 Pages PDF
Keywords
AEACHDAmmineAdiabatic electron affinityΔGCBDCAIEDissociative electron transferHomohighest occupied molecular orbitalChange in free energyTransition stateFree radicalsCellular toxicityLUMOMolecular orbital calculations
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
Preview
Platinum anti-cancer drugs: Free radical mechanism of Pt-DNA adduct formation and anti-neoplastic effect
Authors
Clifford W. Fong,
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Journal: Free Radical Biology and Medicine
Related Categories
AEA
CHD
Ammine
Adiabatic electron affinity
ΔG
CBDC
AIE
Dissociative electron transfer
Homo
highest occupied molecular orbital
Change in free energy
Transition state
Free radicals
Cellular toxicity
LUMO
Molecular orbital calculations
Ageing
Biochemistry
Biochemistry, Genetics and Molecular Biology (General)
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Biotechnology
Cancer Research
Cell Biology
Clinical Biochemistry
Developmental Biology
Endocrinology
Genetics
Molecular Biology
Molecular Medicine
Physiology
Structural Biology
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