Angiotensin(1-7) attenuated Angiotensin II-induced hepatocyte EMT by inhibiting NOX-derived H2O2-activated NLRP3 inflammasome/IL-1Î²/Smad circuit

Article ID	Journal	Published Year	Pages	File Type
8267885	Free Radical Biology and Medicine	2016	44 Pages	PDF

Keywords

ACE2 Nod-like receptor family, pyrin domain containing 3 HSCs NLRP3 NOX4 IL-1R AT1R IL-1RA DPI BDL RAS NAC ECM ASC N-acetylcysteine NADPH oxidase 4 NOx ROS Hydrogen peroxide angiotensin II type 1 receptor angiotensin converting enzyme 2 Angiotensin II Angiotensin-(1–7)NLRP3 inflammasome mesenchymal-epithelial transition NADPH oxidase EMT Ang II diphenylene iodonium Hepatic stellate cells renin-angiotensin system Liver fibrosis Extracellular matrix MET Hepatocyte H2O2 bile duct ligation Epithelial-mesenchymal transition Reactive oxygen species

Related Topics

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Angiotensin(1-7) attenuated Angiotensin II-induced hepatocyte EMT by inhibiting NOX-derived H2O2-activated NLRP3 inflammasome/IL-1Î²/Smad circuit

Authors

Li-Li Zhang, Shan Huang, Xiao-Xin Ma, Wen-Yong Zhang, Dan Wang, Si-Yi Jin, Yan-Ping Zhang, Yang Li, Xu Li,