NOX4-derived reactive oxygen species limit fibrosis and inhibit proliferation of vascular smooth muscle cells in diabetic atherosclerosis

Article ID	Journal	Published Year	Pages	File Type
8267892	Free Radical Biology and Medicine	2016	26 Pages	PDF

Keywords

PCNA TGF STZ ECM PDGF qRT-PCR CTGF OPN Calponin mRNA NOX4 SMC FBS NOx ROS siRNA Atherosclerosis Proliferating Cell Nuclear Antigen Apoe apolipoprotein E LCA Osteopontin streptozotocin small interfering ribonucleic acid NADPH oxidase Diabetes transforming growth factor messenger ribonucleic acid foetal bovine serum Smooth muscle cell Vascular smooth muscle cell left common carotid artery CNN dominant negative Connective tissue growth factor platelet-derived growth factor Extracellular matrix quantitative real-time polymerase chain reaction high glucose normal glucose Reactive oxygen species

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Life Sciences Biochemistry, Genetics and Molecular Biology Ageing

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NOX4-derived reactive oxygen species limit fibrosis and inhibit proliferation of vascular smooth muscle cells in diabetic atherosclerosis

Authors

Elyse Di Marco, Stephen P. Gray, Kit Kennedy, Cedric Szyndralewiez, Alicia N. Lyle, Bernard LassÃ¨gue, Kathy K. Griendling, Mark E. Cooper, Harald H.H.W. Schmidt, Karin A.M. Jandeleit-Dahm,