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DDAH1 deficiency promotes intracellular oxidative stress and cell apoptosis via a miR-21-dependent pathway in mouse embryonic fibroblasts

Article ID Journal Published Year Pages File Type
8268079 Free Radical Biology and Medicine 2016 30 Pages PDF
Keywords
APCsqRT-PCRGSSGNOSMEFsGSHSOD2GFPDDAHDDAH1MnTBAPtBHPADMAROSOxidative stressDimethylarginine dimethylaminohydrolaseasymmetric dimethylarginineRONSSODTempolSuperoxide dismutasemouse embryonic fibroblastsMicroRNAMiRNAknockoutwild typeNitric oxidenitric oxide synthasetert-butyl hydroperoxidequantitative real-time PCRgreen fluorescent proteinreduced glutathioneoxidized glutathioneReactive oxygen and nitrogen speciesReactive oxygen species
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
Preview
DDAH1 deficiency promotes intracellular oxidative stress and cell apoptosis via a miR-21-dependent pathway in mouse embryonic fibroblasts
Authors
Chenyang Zhao, Tianhe Li, Bingxing Han, Wenhui Yue, Linlin Shi, Hongyun Wang, Yuting Guo, Zhongbing Lu,
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Journal
Free Radical Biology and Medicine
Journal: Free Radical Biology and Medicine
Related Categories
APCs
qRT-PCR
GSSG
NOS
MEFs
GSH
SOD2
GFP
DDAH
DDAH1
MnTBAP
tBHP
ADMA
ROS
Oxidative stress
Dimethylarginine dimethylaminohydrolase
asymmetric dimethylarginine
RONS
SOD
Tempol
Superoxide dismutase
mouse embryonic fibroblasts
MicroRNA
MiRNA
knockout
wild type
Nitric oxide
nitric oxide synthase
tert-butyl hydroperoxide
quantitative real-time PCR
green fluorescent protein
reduced glutathione
oxidized glutathione
Reactive oxygen and nitrogen species
Reactive oxygen species
Ageing
Biochemistry
Biochemistry, Genetics and Molecular Biology (General)
Biophysics
Biotechnology
Cancer Research
Cell Biology
Clinical Biochemistry
Developmental Biology
Endocrinology
Genetics
Molecular Biology
Molecular Medicine
Physiology
Structural Biology
Related Journals
Neurobiology of Aging
Revista Española de Geriatría y Gerontología
Ageing Research Reviews
Archives of Gerontology and Geriatrics
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Experimental Gerontology
Journal of Geriatric Oncology
Journal of the Neurological Sciences
Maturitas
Mechanisms of Ageing and Development
Parkinsonism & Related Disorders
Redox Biology
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