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2-Methoxy-6-acetyl-7-methyljuglone (MAM), a natural naphthoquinone, induces NO-dependent apoptosis and necroptosis by H2O2-dependent JNK activation in cancer cells

Article ID Journal Published Year Pages File Type
8268085 Free Radical Biology and Medicine 2016 55 Pages PDF
Keywords
FLRJC-1DAF-FMDCFH2-DADPIhpfhighly reactive oxygen speciesiNOSERKCATc-Jun-N-terminal kinaseL-NMMAJnkHydroxyphenyl fluorescein2′,7′-dichlorodihydrofluorescein diacetate5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazolylcarbocyanine iodideDMSOdihydroethidiumDiphenyleneiodoniumDimethyl sulfoxideinducible nitric oxide synthaseextracellular signal regulated kinasefluorescence detectorDHECatalasehigh-performance liquid chromatographyHPLC
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
Preview
2-Methoxy-6-acetyl-7-methyljuglone (MAM), a natural naphthoquinone, induces NO-dependent apoptosis and necroptosis by H2O2-dependent JNK activation in cancer cells
Authors
Wen Sun, Jiaolin Bao, Wei Lin, Hongwei Gao, Wenwen Zhao, Qingwen Zhang, Chung-Hang Leung, Dik-Lung Ma, Jinjian Lu, Xiuping Chen,
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Journal
Free Radical Biology and Medicine
Journal: Free Radical Biology and Medicine
Related Categories
FLR
JC-1
DAF-FM
DCFH2-DA
DPI
hpf
highly reactive oxygen species
iNOS
ERK
CAT
c-Jun-N-terminal kinase
L-NMMA
Jnk
Hydroxyphenyl fluorescein
2′,7′-dichlorodihydrofluorescein diacetate
5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazolylcarbocyanine iodide
DMSO
dihydroethidium
Diphenyleneiodonium
Dimethyl sulfoxide
inducible nitric oxide synthase
extracellular signal regulated kinase
fluorescence detector
DHE
Catalase
high-performance liquid chromatography
HPLC
Ageing
Biochemistry
Biochemistry, Genetics and Molecular Biology (General)
Biophysics
Biotechnology
Cancer Research
Cell Biology
Clinical Biochemistry
Developmental Biology
Endocrinology
Genetics
Molecular Biology
Molecular Medicine
Physiology
Structural Biology
Related Journals
Neurobiology of Aging
Revista Española de Geriatría y Gerontología
Ageing Research Reviews
Archives of Gerontology and Geriatrics
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Experimental Gerontology
Journal of Geriatric Oncology
Journal of the Neurological Sciences
Maturitas
Mechanisms of Ageing and Development
Parkinsonism & Related Disorders
Redox Biology
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