Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8268127 | Free Radical Biology and Medicine | 2016 | 44 Pages |
Abstract
In summary, oral AA supplementation ameliorates skeletal muscle oxidative stress during hyperinsulinaemia and improves insulin-mediated glucose disposal in people with type 2 diabetes. Findings implicate AA supplementation as a potentially inexpensive, convenient, and effective adjunct therapy in the treatment of insulin resistance in people with type 2 diabetes.
Keywords
TAADCFHFFMGSSGSVCT2GSHEGPDcfGIR2′,7′-dichlorofluorescein2′,7′-dichlorofluorescinHydrogen peroxideAscorbic acidOxidative stressfat-free massEndogenous glucose productionType 2 diabetesRONSSODSuperoxide dismutaseSkeletal muscleglucose infusion rateH2O2reduced glutathioneTotal ascorbic acidglutathione disulphideReactive oxygen and nitrogen species
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Authors
Shaun A. Mason, Paul A. Della Gatta, Rod J. Snow, Aaron P. Russell, Glenn D. Wadley,