1-Methylnicotinamide ameliorates lipotoxicity-induced oxidative stress and cell death in kidney proximal tubular cells

Article ID	Journal	Published Year	Pages	File Type
8268826	Free Radical Biology and Medicine	2015	11 Pages	PDF

Keywords

HO-1 NMN PARP NAMPT PAI-1 MnSOD PTC Nicotinamide adenine dinucleotide (NAD)MCP-1 SAM FFA 1-methylnicotinamide NNMT 4-HNE PBS Heme oxigenase-1 nicotinamide N-methyltransferase 4-hydroxy-2-nonenal BSA short interfering RNA ROS S-adenosyl-L-methionine siRNA bovine serum albumin Free fatty acid ESRD یا end stage renal disease Terminal deoxynucleotidyl transferase dUTP nick end labeling TUNEL Apoptosis proximal tubular cell Lipotoxicity manganese superoxide dismutase Phosphate buffered saline end stage renal disease Plasminogen activator inhibitor-1 NAD Necrosis nicotinamide adenine dinucleotide nicotinamide phosphoribosyltransferase nicotinamide mononucleotide polymerase chain reaction PCR monocyte chemoattractant protein-1 Proteinuria poly (ADP-ribose) polymerase Reactive oxygen species

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Life Sciences Biochemistry, Genetics and Molecular Biology Ageing

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1-Methylnicotinamide ameliorates lipotoxicity-induced oxidative stress and cell death in kidney proximal tubular cells

Authors

Yuki Tanaka, Shinji Kume, Hisazumi Araki, Jun Nakazawa, Masami Chin-Kanasaki, Shin-ichi Araki, Fumiyuki Nakagawa, Daisuke Koya, Masakazu Haneda, Hiroshi Maegawa, Takashi Uzu,