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Hemoglobin-induced lung vascular oxidation, inflammation, and remodeling contribute to the progression of hypoxic pulmonary hypertension and is attenuated in rats with repeated-dose haptoglobin administration

Article ID Journal Published Year Pages File Type
8269330 Free Radical Biology and Medicine 2015 37 Pages PDF
Keywords
IronSickle cell diseaseThalassemiaFree radicalsHemeHemolysisHemoglobinLipid peroxidation
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
Preview
Hemoglobin-induced lung vascular oxidation, inflammation, and remodeling contribute to the progression of hypoxic pulmonary hypertension and is attenuated in rats with repeated-dose haptoglobin administration
Authors
David C. Irwin, Jin Hyen Baek, Kathryn Hassell, Rachelle Nuss, Paul Eigenberger, Christina Lisk, Zoe Loomis, Joanne Maltzahn, Kurt R. Stenmark, Eva Nozik-Grayck, Paul W. Buehler,
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Journal
Free Radical Biology and Medicine
Journal: Free Radical Biology and Medicine
Related Categories
Iron
Sickle cell disease
Thalassemia
Free radicals
Heme
Hemolysis
Hemoglobin
Lipid peroxidation
Ageing
Biochemistry
Biochemistry, Genetics and Molecular Biology (General)
Biophysics
Biotechnology
Cancer Research
Cell Biology
Clinical Biochemistry
Developmental Biology
Endocrinology
Genetics
Molecular Biology
Molecular Medicine
Physiology
Structural Biology
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