Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8269432 | Free Radical Biology and Medicine | 2015 | 8 Pages |
Abstract
Peroxiredoxins were not recognized as a family of enzymes until the 1990s but are now known to be the dominant peroxidases in most organisms. Here, the history and fundamental properties of peroxiredoxins are briefly reviewed, with a special focus on describing how an exquisitely tunable balance between fully folded and locally unfolded conformations plays a large role in peroxiredoxin catalytic properties.
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Authors
P. Andrew Karplus,