Redox regulation of antioxidants, autophagy, and the response to stress: Implications for electrophile therapeutics

Article ID	Journal	Published Year	Pages	File Type
8270154	Free Radical Biology and Medicine	2014	12 Pages	PDF

Keywords

HSF1 UPR NNT ATG IRE1 LC3 Hsp G6PDH ATF6 NOS ANT Sequestosome-1 HSR HSE HNE mTOR ESR AMPK LKB1 ALDH2 4-hydroxynonenal GAPDH inositol-requiring protein-1 EMA Nrf2 GST AMP-activated protein kinase keap1 GRP78/BiP NOx p62/SQSTM1 ROS aldehyde dehydrogenase 2 Aldose reductase malic enzyme European Medicines agency Autophagy Electrophiles NADPH oxidase Chronic obstructive pulmonary disease COPD nicotinamide nucleotide transhydrogenase ATM microtubule-associated protein light chain 3 Bioenergetics endoplasmic reticulum heat shock element Heat shock factor-1 activating transcription factor 6 Multiple sclerosis nitric oxide synthase mammalian target of rapamycin Heat shock response Unfolded protein response 78-kDa glucose-regulated protein Heat shock protein PERK liver kinase B1 glucose-6-phosphate dehydrogenase glyceraldehyde-3-phosphate dehydrogenase Reactive oxygen species

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Redox regulation of antioxidants, autophagy, and the response to stress: Implications for electrophile therapeutics

Authors

Anna-Liisa Levonen, Bradford G. Hill, Emilia Kansanen, Jianhua Zhang, Victor M. Darley-Usmar,