Rhein exerts pro- and anti-inflammatory actions by targeting IKKÎ² inhibition in LPS-activated macrophages

Article ID	Journal	Published Year	Pages	File Type
8270171	Free Radical Biology and Medicine	2014	9 Pages	PDF

Keywords

NF-κB IL-1β LPS IL-6 PGE2 caspase-1 AP-1 iNOS HMGB1 IKK IκB kinase IκB kinase β O2−superoxide anion Osteoarthritis interleukin-6 Interleukin-1β tumor necrosis factor-α Free radicals Rhein SOD inducible nitric oxide synthase Superoxide dismutase TNF-α nuclear factor-κB lipopolysaccharide Macrophages activator protein-1 Prostaglandin E2

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Rhein exerts pro- and anti-inflammatory actions by targeting IKKÎ² inhibition in LPS-activated macrophages

Authors

Yuan Gao, Xi Chen, Lei Fang, Fen Liu, Runlan Cai, Cheng Peng, Yun Qi,