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A novel small molecule that induces oxidative stress and selectively kills malignant cells

Article ID Journal Published Year Pages File Type
8270750 Free Radical Biology and Medicine 2014 12 Pages PDF
Keywords
DemDSBcarboxy-H2DCFDA6-carboxy-2′,7′-dichlorodihydrofluorescein diacetatetBHPDcfNrf2BSOdichlorofluoresceinNACDTNB3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideMTTN-acetylcysteineROSl-ascorbic aciddithiobis-2-nitrobenzoic acidbuthionine sulfoximinetert-Butyl hydrogen peroxideOxidative stressdiethyl maleateCancerdouble-strand breaksNF-E2-related factor 2leukemiaCell deathPropidium iodideGlutathioneReactive oxygen species
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
Preview
A novel small molecule that induces oxidative stress and selectively kills malignant cells
Authors
Francesca R. Å alipur, E. Merit Reyes-Reyes, Bo Xu, Gerald B. Hammond, Paula J. Bates,
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Journal
Free Radical Biology and Medicine
Journal: Free Radical Biology and Medicine
Related Categories
Dem
DSB
carboxy-H2DCFDA
6-carboxy-2′,7′-dichlorodihydrofluorescein diacetate
tBHP
Dcf
Nrf2
BSO
dichlorofluorescein
NAC
DTNB
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
MTT
N-acetylcysteine
ROS
l-ascorbic acid
dithiobis-2-nitrobenzoic acid
buthionine sulfoximine
tert-Butyl hydrogen peroxide
Oxidative stress
diethyl maleate
Cancer
double-strand breaks
NF-E2-related factor 2
leukemia
Cell death
Propidium iodide
Glutathione
Reactive oxygen species
Ageing
Biochemistry
Biochemistry, Genetics and Molecular Biology (General)
Biophysics
Biotechnology
Cancer Research
Cell Biology
Clinical Biochemistry
Developmental Biology
Endocrinology
Genetics
Molecular Biology
Molecular Medicine
Physiology
Structural Biology
Related Journals
Neurobiology of Aging
Revista Española de Geriatría y Gerontología
Ageing Research Reviews
Archives of Gerontology and Geriatrics
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Experimental Gerontology
Journal of Geriatric Oncology
Journal of the Neurological Sciences
Maturitas
Mechanisms of Ageing and Development
Parkinsonism & Related Disorders
Redox Biology
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