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Translocation of iron from lysosomes to mitochondria during ischemia predisposes to injury after reperfusion in rat hepatocytes

Article ID Journal Published Year Pages File Type
8271064 Free Radical Biology and Medicine 2013 11 Pages PDF
Keywords
TMRMLTRKRHMPTKrebs–Ringer–HEPESLysoTracker RedV-ATPaseMCUOH•ROSΔψIronmitochondrial permeability transitionIschemiaischemia–reperfusionFree radicalsHydroxyl radicalLysosomeMitochondrial Ca2+ uniportertetramethylrhodamine methyl esterCell deathMitochondriaMitochondrial membrane potentialPropidium iodideReactive oxygen species
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
Preview
Translocation of iron from lysosomes to mitochondria during ischemia predisposes to injury after reperfusion in rat hepatocytes
Authors
Xun Zhang, John J. Lemasters,
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Journal
Free Radical Biology and Medicine
Journal: Free Radical Biology and Medicine
Related Categories
TMRM
LTR
KRH
MPT
Krebs–Ringer–HEPES
LysoTracker Red
V-ATPase
MCU
OH•
ROS
Δψ
Iron
mitochondrial permeability transition
Ischemia
ischemia–reperfusion
Free radicals
Hydroxyl radical
Lysosome
Mitochondrial Ca2+ uniporter
tetramethylrhodamine methyl ester
Cell death
Mitochondria
Mitochondrial membrane potential
Propidium iodide
Reactive oxygen species
Ageing
Biochemistry
Biochemistry, Genetics and Molecular Biology (General)
Biophysics
Biotechnology
Cancer Research
Cell Biology
Clinical Biochemistry
Developmental Biology
Endocrinology
Genetics
Molecular Biology
Molecular Medicine
Physiology
Structural Biology
Related Journals
Neurobiology of Aging
Revista Española de Geriatría y Gerontología
Ageing Research Reviews
Archives of Gerontology and Geriatrics
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Experimental Gerontology
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Journal of the Neurological Sciences
Maturitas
Mechanisms of Ageing and Development
Parkinsonism & Related Disorders
Redox Biology
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