Peptides that activate the 20S proteasome by gate opening increased oxidized protein removal and reduced protein aggregation

Article ID	Journal	Published Year	Pages	File Type
8271093	Free Radical Biology and Medicine	2014	10 Pages	PDF

Keywords

ChT-L NMM TBTU O-(benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate HOBt PAP AmC Suc-LLVY-AMC TFA DTT DMF FITC DNPH 2,4-dinitrophenylhydrazine 4-Methylmorpholine 7-amido-4-methylcoumarin DMSO N,N-dimethyl formamide amyotrophic lateral sclerosis familial amyotrophic lateral sclerosis Trifluoroacetic acid Protein oxidation ALS protein aggregation fALS dithiothreitol Dimethyl sulfoxide Free radicals SOD Superoxide dismutase Mass spectrometry fluorescein isothiocyanate wild type Proteasome 26S proteasome Propidium iodide 20S proteasome Therapeutic peptides

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Peptides that activate the 20S proteasome by gate opening increased oxidized protein removal and reduced protein aggregation

Authors

Francisco H. Dal Vechio, Fernanda Cerqueira, Ohara Augusto, Robson Lopes, Marilene Demasi,