Article ID Journal Published Year Pages File Type
8271234 Free Radical Biology and Medicine 2013 12 Pages PDF
Abstract
► Eupomatenoid-5 has trypanocidal activity in three parasitic forms of T. cruzi. ► Eupomatenoid-5 induces reduction of trypanothione reductase activity in T. cruzi. ► Eupomatenoid-5 induces increase in the formation of oxidant species in T. cruzi. ► Eupomatenoid-5 induces mitochondrial depolarization in T. cruzi. ► Eupomatenoid-5 induces oxidative imbalance in T. cruzi followed by parasite death.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
Authors
, , , , , ,