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Mitochondrial genome depletion in human liver cells abolishes bile acid-induced apoptosis: Role of the Akt/mTOR survival pathway and Bcl-2 family proteins

Article ID Journal Published Year Pages File Type
8271350 Free Radical Biology and Medicine 2013 11 Pages PDF
Keywords
DCFH-DAGCDCAmt-ND1BSEPBcrpEtBrMRPABCERKGSHMDRMMPDCA2′,7′-dichlorofluorescein diacetateMitochondrial DNAAktethidium bromideDeoxycholic acidGlycochenodeoxycholic acidmtDNAlactate dehydrogenaseLDHHydroethidineMitochondrial membrane potentialmultidrug resistance-associated proteinmultidrug resistance proteinbreast cancer resistance proteinprotein kinase BBile salt export pumpATP-binding cassetteextracellular regulated kinaseGlutathione
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
Preview
Mitochondrial genome depletion in human liver cells abolishes bile acid-induced apoptosis: Role of the Akt/mTOR survival pathway and Bcl-2 family proteins
Authors
Jose J.G. Marin, Alicia Hernandez, Isabel E. Revuelta, Ester Gonzalez-Sanchez, Jose M. Gonzalez-Buitrago, Maria J. Perez,
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Journal
Free Radical Biology and Medicine
Journal: Free Radical Biology and Medicine
Related Categories
DCFH-DA
GCDCA
mt-ND1
BSEP
Bcrp
EtBr
MRP
ABC
ERK
GSH
MDR
MMP
DCA
2′,7′-dichlorofluorescein diacetate
Mitochondrial DNA
Akt
ethidium bromide
Deoxycholic acid
Glycochenodeoxycholic acid
mtDNA
lactate dehydrogenase
LDH
Hydroethidine
Mitochondrial membrane potential
multidrug resistance-associated protein
multidrug resistance protein
breast cancer resistance protein
protein kinase B
Bile salt export pump
ATP-binding cassette
extracellular regulated kinase
Glutathione
Ageing
Biochemistry
Biochemistry, Genetics and Molecular Biology (General)
Biophysics
Biotechnology
Cancer Research
Cell Biology
Clinical Biochemistry
Developmental Biology
Endocrinology
Genetics
Molecular Biology
Molecular Medicine
Physiology
Structural Biology
Related Journals
Neurobiology of Aging
Revista Española de Geriatría y Gerontología
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Experimental Gerontology
Journal of Geriatric Oncology
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Mechanisms of Ageing and Development
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Redox Biology
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