A spontaneous mutation in the nicotinamide nucleotide transhydrogenase gene of C57BL/6J mice results in mitochondrial redox abnormalities

Article ID	Journal	Published Year	Pages	File Type
8271388	Free Radical Biology and Medicine	2013	11 Pages	PDF

Keywords

GPX AcAc SOD2 NNT FCCP Isoc MPT TMPD GSSG acetoacetate 3-Hydroxybutyrate dehydrogenase GSH 3-hydroxybutyrate APAD PCoA NADPH me3 NADP IDH2 3-acetylpyridine adenine dinucleotide antimycin A NAD+NADP+ROS t-BOOH β-nicotinamide adenine dinucleotide β-nicotinamide adenine dinucleotide phosphate mitochondrial permeability transition Isocitrate Tert-butyl alcohol nicotinamide nucleotide transhydrogenase Transhydrogenation Mitochondrial superoxide dismutase NAD NADH tert-butyl hydroperoxide carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone Calcium Glutathione glutathione disulfide glutathione reductase glutathione peroxidase Reactive oxygen species

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A spontaneous mutation in the nicotinamide nucleotide transhydrogenase gene of C57BL/6J mice results in mitochondrial redox abnormalities

Authors

Juliana A. Ronchi, Tiago R. Figueira, Felipe G. Ravagnani, Helena C.F. Oliveira, Anibal E. Vercesi, Roger F. Castilho,