| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8271472 | Free Radical Biology and Medicine | 2013 | 12 Pages |
Abstract
⺠Nitric oxide reacts with hydroxyl radical-induced guanine radicals to form xanthine and 8-azaguanine. ⺠Mechanisms of guanine radical reactions with nitric oxide are discussed. ⺠Radiosensitization of cells by NO may involve DNA base modifications. ⺠The DNA base modifications can lead to replication-induced DNA strand breaks.
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Authors
Lisa K. Folkes, Peter O'Neill,