Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8271476 | Free Radical Biology and Medicine | 2013 | 10 Pages |
Abstract
The results suggest that the inhibition of TrxR1 and TrxR2 at the selenocysteine residue by S3 is responsible for ROS production, which activates FOXO3a, leading to the upregulation of Bim expression.151
Keywords
NF-κBASK1GRsAP1HIF-1αdithiobisnitrobenzoic acidDNCBN-acetyl-l-cysteineCBBDTNBNACMEFDMEM3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideCoomassie Brilliant BlueDulbecco's modified Eagle's mediumMTTDinitrochlorobenzenehypoxia-inducible factor 1αmouse embryonic fibroblastactivator protein-1apoptosis signal-regulating kinase 1
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Authors
Jinhua Liu, Chenglong Mu, Wen Yue, Jie Li, Biao Ma, Lixia Zhao, Lei Liu, Quan Chen, Chen Yan, Haiyang Liu, Xiaojiang Hao, Yushan Zhu,