| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8271578 | Free Radical Biology and Medicine | 2013 | 13 Pages |
Abstract
⺠Nlrp3 inflammasome activation caused by SAA involves mitochondrial reactive oxygen species. ⺠A mechanism by which mitochondrial dysfunction causes sustained IL-1β is proposed. ⺠The mechanism is based on impaired Nlrp3 complex disassembly.
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Authors
Joshua Jabaut, Jennifer L. Ather, Alexandra Taracanova, Matthew E. Poynter, Karina Ckless,