Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8271604 | Free Radical Biology and Medicine | 2013 | 10 Pages |
Abstract
⺠Chlorinated and nitrated HDL have reduced capacity to stimulate endothelial cell (EC) proliferation. ⺠Cl-HDL and NO2-HDL have reduced capacity to stimulate EC migration. ⺠Cl-HDL and NO2-HDL have diminished capacity to activate Akt and ERK1/2 in ECs. ⺠Cl-HDL and NO2-HDL show reduced stimulation of reendothelialization in vivo.
Keywords
SR-BIApoA-IEPCHUVECHDLERK3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideMPOhigh-density lipoproteinMAPK/ERK kinaseMTTApolipoprotein A-IAktOxidationcardiovascular diseaseFree radicalsCVDHuman umbilical vein endothelial cellEndothelial cellEndothelial progenitor cellMEKMigrationprotein kinase BExtracellular regulated protein kinase
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Ageing
Authors
Bing Pan, Baoqi Yu, Hui Ren, Belinda Willard, Ling Pan, Lingyun Zu, Xiaoli Shen, Yijing Ma, Xiuli Li, Chenguang Niu, Jinge Kong, Siyu Kang, Y. Eugene Chen, Subramaniam Pennathur, Lemin Zheng,