Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8271638 | Free Radical Biology and Medicine | 2013 | 11 Pages |
Abstract
⺠Paraoxonase 2 (PON2) is expressed at higher levels in astrocytes and neurons from female mice. ⺠Brain cells from male mice are more susceptible to oxidative stress-induced toxicity. ⺠Estradiol modulates PON2 expression in vitro and in vivo. ⺠Estradiol-induced neuroprotection is not present in cells from PON2-null mice.
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Authors
G. Giordano, L. Tait, C.E. Furlong, T.B. Cole, T.J. Kavanagh, L.G. Costa,