Article ID Journal Published Year Pages File Type
8271638 Free Radical Biology and Medicine 2013 11 Pages PDF
Abstract
► Paraoxonase 2 (PON2) is expressed at higher levels in astrocytes and neurons from female mice. ► Brain cells from male mice are more susceptible to oxidative stress-induced toxicity. ► Estradiol modulates PON2 expression in vitro and in vivo. ► Estradiol-induced neuroprotection is not present in cells from PON2-null mice.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
Authors
, , , , , ,