Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8271663 | Free Radical Biology and Medicine | 2013 | 12 Pages |
Abstract
⺠Pathways and products of COX-AA/DGLA peroxidation were confirmed in a cell model. ⺠Radicals were characterized and quantified under normal cell culture conditions. ⺠Association between free radicals and cell growth response was assessed. ⺠This approach allows other research labs to conduct radical studies in similar cell models.
Keywords
COXPOBNeXtracted Ion CurrentHOAcDGLATICACNESRESR spin trappingLC/MScyclooxygenaseAcetonitrileArachidonic acidglacial acetic acidPolyunsaturated fatty acidPUFAtotal ion currentFree radicalsElectron spin resonanceRetention timeMass spectrometryEICprostaglandinhigh-performance liquid chromatographyHPLC
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Authors
Yan Gu, Yi Xu, Benedict Law, Steven Y. Qian,