| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8272532 | Journal of the Neurological Sciences | 2018 | 10 Pages |
Abstract
Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune inflammatory disorder of the central nervous system (CNS). Serum immunoglobulin G autoantibodies (NMO-IgG) are identified in the majority of NMOSD patients. The Pediatric form presents before 18â¯years. Based on the similarity of clinical, neuroimaging, and laboratory characteristics of pediatric NMOSD to those of the adult form, the international panel suggested that adult criteria of NMOSD also are appropriate in pediatric patients. However, the proposed criteria need validation in pediatric patients. This strategy poses challenges to the study design in clinical trials in pediatric NMOSD patients.
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Authors
Seyed Mohammad Baghbanian, Nasrin Asgari, Mohammad Ali Sahraian, Abdorreza Naser Moghadasi,