Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8273138 | Journal of the Neurological Sciences | 2017 | 8 Pages |
Abstract
After supratentorial cerebral infarction, the expressions of RGMb and synaptophysin were up-regulated in rats, neurofilament protein (NF-200) expression was decreased, and MRI parameters (ADC and FA values) were reduced, indicating that RGMb protein may be involved in the regeneration and remodeling of axons and synapses, and exert an important role in pathophysiological processes such as nerve regeneration disturbance and neuron apoptosis after cerebral ischemia injury. In vivo MRI can be a noninvasive technique to monitor the areas of cerebral infarction and the recovery of neurological function.
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Authors
Xiao Wang, Jing-Liang Cheng, Yun-Cai Ran, Yong Zhang, Lu Yang, Ya-Nan Lin,