Extracellular miR-145, miR-223 and miR-326 expression signature allow for differential diagnosis of immune-mediated neuroinflammatory diseases

Article ID	Journal	Published Year	Pages	File Type
8273231	Journal of the Neurological Sciences	2017	36 Pages	PDF

Abstract

miR-145, miR-223 and miR-326expression profile allows for differential diagnosis of immune-mediated neuroinflammatory diseases: MS from NMOSD (A), MS from NPSLE (B), NMOSD from NPSLE (C) and RRMS from SPMS (D).102

Keywords

AQP4 MSSS Multiple Sclerosis Severity Score NMOSD SPMS IKKα RRMs Smad3 IL-17 SIRPα EDSS Aquaporin-4 NPSLE qRT-PCR CD47 ROC miRNAs IgG NF-κB cDNA Complementary DNA Sp1 Neuromyelitis optica spectrum disorder MRI immunoglobulin G interleukin-17 Magnetic resonance imaging microRNAs nuclear factor kappa B Neuropsychiatric systemic lupus erythematosus Specificity protein 1 Expanded Disability Status Scale secondary progressive multiple sclerosis relapsing-remitting multiple sclerosis Multiple sclerosis quantitative real-time polymerase chain reaction receiver operating characteristic

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Extracellular miR-145, miR-223 and miR-326 expression signature allow for differential diagnosis of immune-mediated neuroinflammatory diseases

Authors

Wessam E. Sharaf-Eldin, Nirmeen A. Kishk, Yehia Z. Gad, Heba Hassan, Mohamed A.M. Ali, Maha S. Zaki, Mohamed R. Mohamed, Mona L. Essawi,