Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8274188 | Journal of the Neurological Sciences | 2016 | 7 Pages |
Abstract
Plasma donepezil concentration correlated positively with change in cognitive function without affecting safety, and was affected mainly by dose and to a lesser extent by age. Therefore, for patients in whom safety concerns are not found at donepezil 5Â mg/day, increasing the dose to 10Â mg/day to increase plasma concentration is worthwhile to further improve cognitive function.
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Authors
Etsuro Mori, Manabu Ikeda, Kenya Nakai, Hideaki Miyagishi, Masaki Nakagawa, Kenji Kosaka,