| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8275701 | Journal of the Neurological Sciences | 2015 | 6 Pages |
Abstract
This study confirms the translational potential of CED of MANF as a novel treatment strategy in PD and also supports the co-infusion of gadolinium as a proxy measure of MANF distribution in future clinical studies. Further study is required to determine the optimum infusion regime, flow rate and frequency of infusions in human trials.
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Authors
N.U. Barua, A.S. Bienemann, M. Woolley, M.J. Wyatt, D. Johnson, O. Lewis, C. Irving, G. Pritchard, S. Gill,