| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8276427 | Journal of the Neurological Sciences | 2015 | 7 Pages |
Abstract
Supposed to be fibrin-specific, rt-PA induces a decrease in circulating fibrinogen, significantly linked to a decrease in plasminogen. A collateral increase in antifibrinolytic agents such as factor XIII and alpha2-antiplasmin is also observed. At 2Â h, a significant decrease in plasminogen and a significant increase in fibrin(ogen) degradation products (FDP) are observed in cardioembolic infarcts, and appear as early independent predictors of this aetiology. A low plasminogen value at 2Â h is potentially predictive of poor prognosis at 3Â months.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Ageing
Authors
Xuhong Sun, Julien Berthiller, Laurent Derex, Paul Trouillas, Laho Diallo, Michel Hanss,